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CLINICAL EVALUATION OF GUDUCHI GHANA VATI AND SHILAJATU VATI IN MADHUMEHA W.S.R. TO NIDDM

Dr. Samsul Islam, Dr. Shripathi Acharya

Vol. 7, Jan-Jun 2019

Abstract:

Background: In diabetes sometimes the disease become resistant to the treatment even by conventional system of medicine Hence there is an urgent need to develop effective and affordable Ayurvedic drug or treatment module in this disease. Hence an effort has been made to evaluate the effect of guduchighanavati and silajatuvati in cases of NIDDM. Guduchi is reported as a highly potent anti diabetic herb and Silajatu as a Naimittika Rasayana for Madhumeha. Aim: The aim of this study is to evaluate combined effect of Guduchi Ghana Vati & Shilajatu Vati in Madhumeha. Materials and Methods: A minimum of 40 patients suffering from Madhumeha were selected after thorough history taking, clinical assessment and laboratory investigation from IPD & OPD of MIAMS to evaluate the Guduchi Ghana Vati(500mg), Shilajatu Vati(250mg) and Guduchi Ghana Vati(500mg) alone in GroupA & group B Patients. Statistical Analysis: The results were statistically interpreted using Student’s ‘t’-test for paired and unpaired data to assess the statistical signifiance and the signifiant level was set at P < 0.05. Results: GGV and SV showed mild reduction in FBS 32% , PPBS 40%, urine Sugar 61%, Lipid Profile(Total Cholesterol)31% and overall 95% improved in GroupA and GGV(Control Drug) FBS 20% , PPBS 28%, urine Sugar 60%, Lipid Profile(Total Cholesterol) 27% and overall 80% improved. Conclusion: After evaluating the observation of the present series of investigation it is concluded that Guduchi Ghana Vati and Shilajatu Vati has a beneficial role in reducing the severity of all the Subjective & Objective Parameter. The Trial group drug showed good tolerability with high acceptance without any adverse drug reaction. The use of Guduchi Ghana Vati and Shilajatu vati provides better alternative which are usually less toxic and affordable.

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