Indu M Menon, M S Deepa
Vol. 8, Jul-Dec 2019
Abstract:
Introduction:All medicinal plants are a rich source of various bioactive chemical constituents. Phytochemical analysis of these plants has a major role in determining the pharmacological action. Some of the main phytochemicals that medicinal plants contain includes alkaloids, polyphenols, steroids, etc. Guggulu, oleo gum resin of the plant Commiphorawightii, is an extensively using Ayurvedic drug, owing to its varied therapeutic effects like anti-inflammatory,anti-obesity,anti-arthritic,wound healing etc. One of its major pharmacological action is vranaharatvam, which can be correlated to wound healing property. Aim:This paper attempts to substantiate this activity with the help of phytochemical evaluation and Ayurvedicperspective. Materials and Methods:Guggulu was collected from its natural habitat and preliminary phytochemical screening including qualitative analysis of metabolites,High performance thin layer chromatography,Atomicabsorbtion Spectroscopy was performed. Results:Phytochemical analysis revealed the presence of tannins,flavonoids,alkaloids,iron,sugars and steroids like guggulsterone E & Z. All the phytochemicals has established and proven effects on wound healing. Karma of Guggulu as per Ayurvedic literatures indicates that Guggulu is beneficial as vranashodhana-ropana-sandhana. This was suggestive of its vranaharaviz wound healing property as revealed through extensive literature surveys done for the study. Conclusion:The present study unveils the vranaharaviz wound healing action of Guggulu by Phytochemical analysis and Ayurvedic pharmacology. It was recognized that a drug’s pharmacological actions can be interpreted from the phytochemical analysis.