Akeel. Shamran Tushy, Dr. Abdul-Rassol Khairallah Saaeed, Dr. Wissam Ali Ameen Awad
Vol. 10, Jul-Dec 2020
Abstract:
The pruritus of scabies are an allergic reaction to the mites. IgE, and eosinophils are essential components of allergic inflammation. In this study showed a high significant correlation between the prostaglandin E2 (PGE2) and leukotriene B4 (LKB4) concentration of scabies patients vs the healthy persons. In scabies group patients the PGE2 was (409±184),while in control group the PGE2 was (80.65±17.9)and in scabies patients LKB4 was (322±149) while in control group was (551±43), with high significant relation (P< 0.05), for both parameters. The relationship between PGE2 and LKB4 is a reverse relationship that when the PGE2 concentration was rises, the LKB4 concentration falls in plasma samples, during the scabies infection The elevated in IgE and Eosinophil cell together in scabies disease ,at high significant correlation between the eosinophil cell and IgE antibody levels of scabies patients vs the healthy persons (P<0.001 ).