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Maternal Antepartal TSH Effect on the Progress of Labour

Shaymaa S. Nayyef, Maha R. Darweesh, Alaa F. Ibraheem

Vol. 10, Jul-Dec 2020

Abstract:

Objective: To evaluate the effect of maternal thyroid stimulating hormone TSH measurement on the need for emergency cesarean section in labour and establish a reference TSH antepartum range for optimal outcome. Study design: prospective observational Study setting: AlKarkh Maternity Hospital Material and Method: A total of 100 term pregnant women admitted to labour ward with signs of labour were included in this study. We excluded women with diabetes, obesity, high blood pressure and known thyroid diseases. A blood sample was drowning for TSH evaluation to all laboring women, who were followed up and the outcome was noted. TSH values compared between two groups, the first group having a successful vaginal birth, the second group having an emergency cesarean section. Additionally, rates of newborn admission to intensive care unit NICU were also studied. Variables like patient’s age, parity, gestational length and newborn birth weight all assessed for correlation with TSH levels. Reference ranges assessed for a successful vaginal birth by identification of 5th and 95th percentiles. Patient consent was taken and documented in clinical notes. Conclusions: There is a significant effect of TSH level in maternal blood antepartum on the progress of labour, with higher mean TSH having more risk for failed progress, emergency cesarean section and newborn admission to intensive care.

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