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Assessment of Serum Neuregulin 4 Level and Several Metabolic Parameter in Gestational Diabetes

Prof. Dr. Maha Mohammed Jasim Al-Bayati, Dr. Noor Ghazi Saleh

Vol. 16, Jul-Dec 2023


Background: The prevalence of gestational diabetes mellitus has increased dramatically during the previous few decades. Neuregulin 4 is a new protein that protects against diet-induced insulin resistance and steatosis in the liver. Neuregulin 4 levels in subcutaneous and visceral adipose tissues were significantly lower in patients with impaired glucose tolerance or diabetes than in healthy people, according to a recent study. Aim: To evaluate the clinical significance of serum Neuregulin 4 and other metabolic parameters in gestational diabetes mellitus. Methods: A casecontrol study was conducted during the period from February to October 2021. The study included 90 pregnant women in the second trimester and was divided into two groups; the gestational diabetes mellitus group (included 45 women who presented with gestational diabetes during current pregnancy) and control group (included 45 healthy pregnant women matched for age, gestational age). Neuregulin 4 and other parameters were measured in the two groups.

DOI: http://doi.org/10.37648/ijrmst.v16i01.012

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