Dr. Dhirendra Kumar Sah, Dr. Ruby Singh, Dr Anil Kumar Pandit, Dr. Mohammad Jiyaul Haq
Vol. 20, Issue 1, Jul-Dec 2025
Abstract:
Endometrial cancer (EC) is a significant health concern, yet its prevalence in Nepal, particularly in the Janakpur region, remains underreported. This study aims to assess the prevalence, clinical characteristics, and associated risk factors of EC in Janakpur, Nepal
A retrospective descriptive study was conducted in three hospitals in Janakpur—Binaytara Foundation Cancer Center, Civil Service Hospital, and National Cancer Hospital. The study analyzed 105 histopathologically confirmed cases of EC diagnosed between April 1, 2021, and January 1, 2024. Patient records were reviewed to obtain demographic data, clinical presentations, histological subtypes, treatment modalities, and follow-up outcomes. Patients were monitored for five years to track disease progression, recurrence, and mortality.
The mean age of diagnosis was 56.19 years, with a range of 40–70 years. A majority of patients (81.90%) were postmenopausal, and 61% resided in urban areas. The most common presenting symptom was postmenopausal bleeding (81.90%). Endometrioid adenocarcinoma was the predominant histological type (86%), followed by serous carcinoma (8%) and carcinosarcoma (3%). Stage I disease was observed in 51.43% of cases, while 34.28% were diagnosed at advanced stages (Stage III & IV). Obesity (34.29%) and hypertension (18.10%) were the most common comorbidities.
The mean age of diagnosis was 56.19 years, with a range of 40–70 years. A majority of patients (81.90%) were postmenopausal, and 61% resided in urban areas. The most common presenting symptom was postmenopausal bleeding (81.90%). Endometrioid adenocarcinoma was the predominant histological type (86%), followed by serous carcinoma (8%) and carcinosarcoma (3%). Stage I disease was observed in 51.43% of cases, while 34.28% were diagnosed at advanced stages (Stage III & IV). Obesity (34.29%) and hypertension (18.10%) were the most common comorbidities.
DOI: http://doi.org/10.37648/ijrmst.v20i01.003
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