Dr. Sailaja Ratna V, Dr. Swapna Bhat
Vol. No. 21, Special Issue No 2 2026
Abstract:
Background: Rhaphidophora pertusa (Roxb.) Schott, a perennial climber belonging to the family Araceae, is traditionally used in folklore medicine for wound healing and inflammatory conditions. Objective: The present study was undertaken to scientifically evaluate the wound healing activity of Rhaphidophora pertusa (Roxb.) Schott Patra Swarasa using experimental wound models in Wistar albino rats. Materials and Methods: Pharmacognostical evaluation, physicochemical analysis, phytochemical screening, and HPTLC profiling were carried out. Acute oral and dermal toxicity studies were conducted as per OECD guidelines. Wound healing activity was assessed using excision wound models. Parameters such as wound contraction, epithelialization period, and histopathology were evaluated. Results: The test drug showed no signs of toxicity. Significant improvement in wound contraction, reduced epithelialization period were observed in test group compared to standard and control. Histopathological findings revealed enhanced collagen deposition and angiogenesis. Conclusion: The study confirms the wound healing potential of Rhaphidophora pertusa (Roxb.) Schott, supporting its traditional use and justifying its consideration as an Anukta Dravya in Ayurveda.
DOI: http://doi.org/10.37648/ijrmst.v21i02.021
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