Dr.Sanjay Prakash
Vol. 6, Issue 1, Jul-Dec 2018
Abstract:
Diabetes mellitus is a clinical syndrome characterized by hyperglycaemia due to absolute or relative deficiency of insulin. Ayurvedic ancient texts have mentioned Meshashringi (Gymnema sylvestre R.Br.) Family: Asclepiadaceae, is a diffuse, twining shrubs with pubescent young parts having an antidiabetic property. As this is having Laghu, Ruksha Guna, Kashaya, Tikta Rasa, Katu Vipaka, Ushna Virya. By the virtue of above properties this is Kaphavatashamaka. It is commonly known as Gurhmar. Plant occurs naturally in various regions of India from Konkan to Travancore. Meshashringi contains two resins, ablbuminous substance, colouring matter, calcium oxalate, gymnemic acid 6%, quercitol and sugar yeast. Ash contains ferric oxide, manganese and other matters. It is used in diabetes insipidus and diabetes mellitus in particular for which leaves powder is prescribed as a single drug or as an ingredient of a recipe. Roots decoction is orally given in case of snake-bite. The drug is bitter tonic. Seeds are useful in coryza, cold, cough and asthma. The present review is therefore, an effort to give a detailed focus on its botanical details, phytochemistry, pharmacodynamics, etiopathogenesis and its therapeutic importance.